Mathuscha Ratnasingham

I am a second-year PhD student under the NIHR BRC Leicester PhD Fellowship, specialising in Respiratory Medicine. My research focuses on TRPM7 as a potential therapeutic target for idiopathic pulmonary fibrosis (IPF). I am experienced in a broad range of laboratory techniques including patch clamp electrophysiology, tissue culture, PCR, Western blotting, flow cytometry, mass spectrometry and additional molecular and cellular assays. I have previously undertaken an MRes research project investigating the effects of BK on membrane potential in glioblastoma multiforme under the supervision of Dr. Paul Smith.

Education

PhD in Infection, Immunity and Inflammation

University of Leicester (2023 – present)

NIHR BRC Leicester PhD Fellowship, Respiratory Medicine Theme

• Project: Investigating TRPM7 as a therapeutic target for idiopathic pulmonary fibrosis (IPF)
• Techniques: Patch clamp electrophysiology, qPCR, Western blotting, flow cytometry, MTS assay, immunofluorescence, mass spectrometry
• Developed in-depth expertise in ion channels and fibrosis signalling pathways